Muscling Up the Heart

Muscling up the heart: a preadolescent cardiomyocyte proliferation contributes to heart growth.

Muscling out malaria.

Muscling through AAV immunity.

AAV-1 is one of the most promising vectors for gene delivery to skeletal muscle. In this issue of Blood, Mingozzi and colleagues now demonstrate that AAV-1-mediated gene transfer into human skeletal muscle results in activation of capsid-specific T cells.

Muscling in on the third dimension

The development of a functional three-dimensional model of human skeletal muscle tissue could accelerate progress towards new and personalized treatments for skeletal muscle disorders.

Muscling in on Tissue Engineering